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안정성 시험챔버
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UPS(무정전 동력공급장치)
Parker Pharmacetical Filter
PROPOR SG Filter Cartridges
  • liquid filters
  • polyethersulphone

  • PROPOR SG sterilizing grade filters feature a microbially
    retentive polyethersulphone membrane for fast, reliable and
    cost-effective sterile filtration of pharmaceutical fluids.

    The asymmetric pore structure and high voids volume of the
    PROPOR SG membrane allow high throughputs and
    exceptionally high flow rates compared with competitive PES and
    alternative membranes. Low protein and preservative
    binding properties minimize product loss due to adsorption.

    PROPOR SG filters are optimized for pharmaceutical processing.
    They have low extractable levels and broad chemical
    compatibility across the full pH range including organic solvents.

    Features and Benefits
  • Up to 3.5 times higher flow rates than competitive sterilizing
        grade filters
  • Fully validated and integrity testable membrane for assurance
        of sterility
  • Low binding for minimal product loss
  • MURUS and DEMICAP’s can be gamma-irradiated and autoclaved

  • Performance Characteristics

    Materials of construction
    - Filtration Membrane :
    - Upstream Support :
    - Downstream Support :
    Filter Cartridges
    - Inner Support Core :
    - Outer Protection Cage :
    - End Caps :
    - End Caps Insert :
    316L Stainless Steel
    MURUS Disposable Filter Capsules
    - Core :
    - Sleeve :
    - End Caps Insert :
    - Standard o-rings/gaskets :
    - Capsule Body :
    - Capsules Vent Seals :
    316L Stainless Steel
    DEMICAP Filter Capsules
    - Core :
    - Sleeve :
    - End Caps :
    - Capsule Body :
    - Capsules Vent Seals :
    - Filling Bell :
    Syringe Filters
    - Body : Polypropylene
    Recommended Operating Conditions
    Filter Cartridges
    Up to 70 °C (158 °F) continuous operating temperature and higher short-term temperatures during CIP to the following limits :
    MURUS Disposable Filter Capsules
    Up to 25 °C ( 77 °F) @ 5.5 barg (79.7 psig)
    Up to 60 °C (140 °F) @ 2.8 barg (40.6 psig)

    Parker Hannifin certify that this product complies with the European Council Pressure Equipment Directive (PED) 97/23/ EC Article 3, Paragraph 3 - Sound Engineering Practice (SEP).
    This product is intended for use with Group 1 & 2 Dangerous and Harmless Liquids and Group 2 Harmless Gases at the operating conditions stated in this document : In compliance with PED Article 3, Paragraph 3, SEP, this product does not bear the CE mark.
    DEMICAP Filter Capsules
    Up to 40 °C (104 °F) at line pressures up to 5.0 barg (72 psig).
    Effective Filtration Area (EFA)
    10¨ (250 mm) :
    K Size :
    A Size :
    B Size :
    E Size :
    Syringe ø50 mm :
    0.55 m2
    0.26 m2
    0.20 m2
    0.10 m2
    0.05 m2
    14.50 cm2
    (5.92 ft2)
    (2.79 ft2)
    (2.15 ft2)
    (1.07 ft2)
    (0.53 ft2)
    (2.25 in2)

    PROPOR SG filter cartridges can be sanitized with hot water at up to 90 °C (194 °F) and are compatible with a wide range of chemicals.

    For detailed operational procedures and advice on cleaning and sterilization, please contact the Technical Support Group through your usual Parker domnick hunter contact.
    Food and Biological Safety
    Materials conform to the relevant requirements of 21CFR Part 177 and current USP Plastics Class VI - 121 °C and ISO10993 equivalents.
    Quality Standards
    Pharmaceutical grade products are manufactured in accordance with cGMP, 100% flushed with pharmaceutical grade purified water and integrity tested prior to despatch. A sample of each lot is tested to demonstrate conformity to validated claims.
    PROPOR SG MURUS & DEMICAP disposable filters can be gamma-irradiated up to a maximum dosage of 40 kGy.

    Performance Characteristics
    TOC / Conductivity
    The filtrate quality from a 10¨ (250 mm) PROPOR SG conforms to the requirements of current USP <643> (TOC) and USP <645> (conductivity) within the first 200 ml flush of purified water.
    Aqueous extracts from the 10¨ (250 mm) PROPOR SG contain < 0.25 EU / ml when tested in accordance with the Limulus Amoebocyte Lysate test.
    Non-Volatile Extractables (NVE)
    Total NVEs extracted in the first 5 litre flush of purified water for a 10¨ (250 mm) cartridge are <10 mg.

    Total NVEs extracted in the first 5 litre flush of purified water for an A size 7.9¨ (200 mm) DEMICAP capsule are <5 mg.
    Pharmaceutical Validation
    A full validation guide is available upon request from Laboratory Services Group (LSG).
    Oxidizable Substances
    PROPOR SG filter cartridges meet current USP and EP quality standards for sterile purified water for oxidizable substances following a <1 litre water flush.
    Integrity Test Data
    All filters are integrity testable to the following limits when wet with water and using air as the test gas.

    *Bubble point for 0.1 μm product is in 60/40 v/v IPA/Water.
    Retention Characteristics
    PROPOR SG filter cartridges are validated by bacterial challenge testing with Brevundimonas diminuta to current ASTM F838-05 methodology (107 organisms / cm2 EFA minimum) with typical in-house challenge levels being 1011 organisms per 10¨ (250 mm) filter cartridge.

    Ordering Information